Lifesperience is now Raycommend, which can be found here: Ray Commend
There is no easy way to say this. Hyperkin's latest v2.2 firmware for the Retron 5 is a bug-filled mess which for many people (myself included) will ruin your Genesis experience. As soon as I upgraded, my Genesis carts would no longer be detected by the system, and sometimes, even the other cartridge slots would stop detecting games.
These were carts that worked perfectly fine on prior firmwares. They also work on the original consoles (which I also own) flawlessly. At this time, the Hyperkin website only links you to the v2.2 firmware or strangely enough, the v2.0 beta 6 firmware.
The only fix in my case, was to downgrade back to v2.1 which resolved my issues. Game cartridges once again detected just fine. For those of you out there wondering, downgrading is the easy part. Finding the links for the prior firmware files was the painful part. Luckily, the pages are still around, and I've linked them below so that others can hopefully resolve their issues.
As previously mentioned, here are the links. Just click to go straight to the download page on their site.
If you need instructions on how to upgrade/downgrade the firmware, here is Hyperkin's video on that process. Once you finish the process, you would be wise to backup your files. These links can be removed at any time, and each system gets a unique file. You cannot use another persons update file to fix your own system.
Hyperkin has been suspiciously mum on the topic of a new firmware file. While there is some mention on their facebook page, I have yet to see an official announcement that something is being worked on. Considering that v2.2 is (as of this article) three months old, that is an eternity when one is waiting for a fix. Shame on them for not being more transparent about this faulty firmware, and any possible planned fix.
My theory is a simple one. With Hyperkin being caught with their pants down over using the libretro code without permission, perhaps they are working to remove all offending code from their firmware. Creating new code, or licensing what is needed will take time, and that's fine, but if this is the case, then let us consumers know what is happening. Then we can make their own decisions.